{
  "metadata": {
    "title": "UroLongevity References, Evidence Notes, and Updates",
    "book_title": "UroLongevity",
    "subtitle": "The Physician's Guide to Healthspan and Precision Aging",
    "author": "David Shusterman, MD",
    "publisher": "UroLongevity Press",
    "series": "The Urologist's Guide",
    "edition_version": "2.1",
    "edition_name": "First Edition",
    "evidence_reviewed_through": "2026-08-13",
    "bibliography_compiled": "2026-08-14",
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      "title": "The Body Speaks in Signals"
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    {
      "number": 2,
      "title": "Not a Steroid, Not a Supplement, Not Snake Oil"
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    {
      "number": 3,
      "title": "The Regulatory Landscape — August 2026 Evidence Review"
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    {
      "number": 4,
      "title": "Reading the Evidence in a Hype-Saturated Field"
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      "number": 5,
      "title": "The Biology of Aging"
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      "number": 6,
      "title": "Semaglutide: More Than a Weight-Loss Drug"
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    {
      "number": 7,
      "title": "Tirzepatide: Two Signals, One Powerful Therapy"
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      "title": "Liraglutide"
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      "title": "Tesamorelin"
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      "title": "Elamipretide"
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      "title": "PT-141 (Bremelanotide)"
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      "title": "Sermorelin"
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      "title": "CJC-1295"
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      "title": "MK-677 (Ibutamoren)"
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      "title": "Thymosin Alpha-1"
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      "title": "TB-500 (Thymosin Beta-4)"
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      "title": "GHK-Cu"
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      "title": "Epitalon"
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      "title": "Retatrutide"
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      "title": "LL-37 and KPV"
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    {
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      "title": "MOTS-c"
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      "title": "Orforglipron"
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    {
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      "title": "NAD⁺ and Its Precursors"
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    {
      "number": 26,
      "title": "Rapamycin and the mTOR Pathway"
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      "title": "Senolytics — Clearing Senescent Cells"
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    {
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      "title": "Testosterone"
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      "title": "Growth Hormone"
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      "title": "Thyroid Hormone"
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      "title": "Female Reproductive Hormones — Perimenopause and Menopause"
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      "title": "DHEA and Adrenal Steroids"
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      "title": "Exercise"
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      "title": "Sleep"
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      "title": "Nutrition"
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      "title": "Mental Work"
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      "title": "Hair Restoration"
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      "title": "Sexual Wellness"
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      "title": "Skin and Aesthetic Interventions"
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      "title": "Bladder, Pelvic Floor, and Continence Rehabilitation"
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      "title": "Early Intervention and the Minimally Invasive Framework"
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    {
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      "title": "The First 90 Days"
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    {
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      "title": "Maintenance — The Long-Term Framework"
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    {
      "number": 47,
      "title": "The Lifespan Framework — Adaptation Across Demographics"
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    {
      "number": 48,
      "title": "The Future of Comprehensive Practice"
    },
    {
      "number": 49,
      "title": "What This Medicine Offers and What It Requires"
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      ],
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        "Semaglutide: More Than a Weight-Loss Drug",
        "Tirzepatide: Two Signals, One Powerful Therapy"
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        "Rapamycin and the mTOR Pathway",
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        "The Lifespan Framework — Adaptation Across Demographics"
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        "The Body Speaks in Signals",
        "Not a Steroid, Not a Supplement, Not Snake Oil"
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        18
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        "TB-500 (Thymosin Beta-4)"
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        "DHEA and Adrenal Steroids"
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        41
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        "Bladder, Pelvic Floor, and Continence Rehabilitation"
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